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Glycopyrrolate (Robinul?, Cuvposa?)
Date: 11/01/2012
BRAND NAMES: Robinul?, Cuvposa?

COMMON USES: Decreases excessive saliva (a non-FDA approved indication) and respiratory (lung) secretions. FDA approved in the treatment of duodenal ulcer and irritable bowel syndrome.

Robinul? is Available in a 1 or 2 milligram (mg) tablet. Also comes in a solution (0.2mg/cc) usually used for injections but which can also be given by mouth.
Cuvposa? is available as a 1mg/5cc oral solution.

HOW IT WORKS: Blocks the activity of acetylcholine (a chemical in the body) at secretory glands, reducing production of saliva and drooling.

THINGS TO DISCUSS WITH YOUR DOCTOR: Don't use if your child has narrow-angle glaucoma, bladder obstruction, or tachycardia (elevated heart rate). Can cause/worsen constipation, limit the body's ability to keep cool by decreasing its ability to sweat, can make swallowing more difficult by reducing amount of saliva, can cause sleep difficulties, and can cause other side effects. Robinul decreases the effectiveness of Sinimet(R). Try to avoid giving it at the same time as antacids or meals in order to help the body better absorb the medicine.

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